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The CD71 antigen is known as the transferrin receptor. It mediates cellular iron uptake via internalization and recycling. It is a type II membrane glycoprotein, characterized as a disulfide-bound dimer of two identical subunits of 95 kDa each. CD71 is expressed on activated T and B lymphocytes, macrophages and erythroblasts. The N-Terminal, intracytoplasmic domain of CD71 mediates rapid endocytosis and self recycling. CD71 is absent from resting blood leucocytes. Its expression is upregulated on proliferating cells.
CD71, T9, Transferrin receptor
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PRODUCT AVAILABILITY AND REGULATORY STATUS DEPENDS ON COUNTRY REGISTRATION PER APPLICABLE REGULATIONS
The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.
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