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Along with CD8α, the CD8β polypeptide molecule is one of the two chains which can be expressed within the CD8 dimer. CD8α is required for surface expression of CD8β. The α and β glycoproteins have similar molecular weights of 32-34 kDa each. The CD8α/β heterodimer is expressed by TCR α/β+ CD8+ T cells whereas TCR γ/δ+ CD8+ T cells and CD8+ NK cells exclusively express the CD8α/α homodimer.
Especificações
Target Species
Human
Specificity
CD8β
Fluorochrome
FITC
Regulatory Status
ASR
Size
1 mL
Format
Liquid
Flow Product Line
IOTest
Clone
2ST8.5H7
Isotype
IgG2a Mouse
Clone Description
The 2ST8.5H7 monoclonal antibody reacts with an epitope formed by the combination of the α and B polypeptides.
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ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
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LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.
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