Beckman.com is conducting maintenance on its shopping cart Friday, July 10th at 9 pm PST thru Sunday, July 12th at 10 pm PST. During this time, orders can still be placed by calling Client Services. We look forward to providing you an improved shopping experience.
The β2-microglobulin is the non-polymorphic non-covalently bound light chain (12 kDa) of the class I major histocompatibility complex (MHC-I) constitutively expressed on the surface of almost all nucleated cell. β2-microglobulin structure, stabilized by a disulfide bound, is similar to an immunoglobulin like domain. β2-microglobulin is required in the endoplasmic reticulum (ER) to associate with the MHC class I heavy molecule to form with other proteins (calreticulin, tapasin, etc.) the loading complex that exits the ER and is transported to the cell surface. After peptide presentation, β2-microglobulin is actively released into circulation.
Isotype: IgG2a Mouse
The B1G6 monoclonal antibody is specific for human β2-microglobulin. It does not react with β2-microglobulin from other species. It recognizes the β2-microglobulin, free or associated with human HLA class I molecules.
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.
Atualmente, não há Documentos Técnicos associados a esta página ou produto. Por favor utilize nossa ferramenta de pesquisa para Documentos Técnicos
Partes e Produtos Relacionados
Oops. The page you wanted could not be found, so we brought you to something similar. If you still can't find what you want, try searching our site instead.