CD244 (2B4) Antigen

The CD244 antigen, also called 2B4, is a 38 kDa cell surface signal transduction molecule found on almost all human NK cells. It induces a granule independent killing mechanism by NK effector cells. It is also found on γδ TCR T cells and approximately half of peripheral αβ TCR CD8+ T cells. It is not found on B or naïve CD8+ T cells. Upon activation, most CD8+ T cells become CD244-positive. However, a small but significant minority of CD8+ T cells remain CD244-negative. This subset is associated with lower cytotoxic activity, lower γ-IFN production and higher IL-4 and IL-10 production. CD244 is a high affinity receptor for CD48.


 Clone: C1.7  Isotype: IgG1 Mouse

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Product Line Specifications

Format Liquid
Specificity CD244
Form PC5.5
Clone C1.7
Isotype IgG1 Mouse
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced B21171

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


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