CD58 Antigen

CD58 is a glycoprotein of 65-70 kDa, either transmembrane or glycosylphosphatidylinositol (GPI)-anchored. CD58 was first described as the lymphocyte-function associated antigen 3 (LFA-3). LFA-3 was further shown to interact with CD2 suggesting an important role in various immunological responses via T-cell adhesion and activation. CD58 activate the costimulation pathways of T lymphocytes and natural killer (NK) cells, maximizing the cytolysis of target cells by cytotoxic T lymphocytes (CTL) and NK cells. This antigen is widely expressed on leucocytes, erythrocytes and endothelial cells.


 Clone: AICD58  Isotype: IgG2a Mouse

The AICD58 antibody is a blocking antibody in LFA-3 mediated adhesion. This antibody was used as a CD58 reference mAb during HLDA 6.
 

Choose a CD58 Model

Product Line Specifications

Format Liquid
Specificity CD58
Form PC5
Clone AICD58
Isotype IgG2a Mouse
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced IM3702

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


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