Cytokeratin Antigen

Cytokeratins belong to the intermediate filament protein family and are characteristic of epithelial cells. At present, more than 20 different cytokeratins have been identified based on the original two dimensional gel electrophoresis classification. A sub classification, based on charge, divides cytokeratins into two subfamilies: the acidic (negatively charged) cytokeratin (type 1) and the neutral to basic (positively charged) cytokeratin (type II). They are typically expressed as pairs, consisting of one acidic and one basic molecule.


 Clone: J1B3  Isotype: IgG1 Mouse

This monoclonal antibody exclusively reacts with cells of epithelial origin, and shows a cytoplasmic staining pattern. It can be used as a gating tool in flow cytometry to distinguish epithelial from non-epithelial cells. Multi-color flow cytometric analysis requires preliminary permeabilization of the cells with digitonin or methanol.
 



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Product Line Specifications

Format Liquid
Specificity Cytokeratin
Form FITC
Clone J1B3
Isotype IgG1 Mouse
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced IM2356U

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


Technical Documents