TCR Vα24 Antigen

TCR Vα24 is also called TCRAV24S1 (according to the nomenclature from Arden et al.) Vα24 is the only described member of the subfamily of the T cell receptor. It has been shown to be expanded in a clonal fashion in the CD3+ CD8- CD4- cell population in PBL of several donors. It is expressed by 0.4% to 1% of peripheral CD3+ cells from normal blood. An invariant Vα24/Vβ11 T cell receptor is expressed in all individuals by clonally expanded CD4– CD8– T cells, reactive to bacterial antigens. This unique lymphocyte population restricted by the CD1d molecule recognition has been identified as the natural killer T (NKT) cells. The IGRa02 sequence is also referred to as TRAV10 (based on the IMGT gene nomenclature).


 Clone: C15  Isotype: IgG1 Mouse

The C15 antibody recognizes the IGRa02 sequence, the only described member of this family.
 

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Product Line Specifications

Format Liquid
Specificity TCR Vα24
Form PC7
Clone C15
Isotype IgG1 Mouse
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced A66907

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


Documentos técnicos