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The CD10 antigen is referred to as the Common Acute Lymphoblastic Leukemia Antigen (CALLA). It is a type II integral membrane protein of 100 kDa, identified as the human membrane-associated neutral endopeptidase (EC3.4.24.11). It is expressed on uncommitted lymphoid precursors. CD10 expression is lost as cells enter the T lineage. In the B lineage, CD10 expression is lost later in ontogeny, as cells acquire surface Ig expression. It is also expressed on activated and proliferating B cells in the germinal center, and on neutrophils as well as on bone marrow stromal cells. It is also expressed on a number of other cells of epithelial origin.
*Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.
Especificações
Target Species
Human
Specificity
CD10
Other Names
CALLA, membrane metallo-endopeptidase
Fluorochrome
APC-Alexa Fluor* 700
Regulatory Status
ASR
Size
0.5 mL
Format
Liquid
Flow Product Line
IOTest
Clone
ALB1
Isotype
IgG1 Mouse
Cross Reactivity
Bovine, Equine
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IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
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RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.
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