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The CD79b molecule (B29, Igβ) is part of the CD79a / CD79b disulphide-linked heterodimer, non-covalently bound to surface immunoglobulins to form B cell receptors (BCR). The molecular weight of CD79b is about 33 to 40 kDa in reducing conditions. The CD79b molecule expression occurs early in B cells ontogeny. It is restricted to B lymphocytes, first appearing on the surface at the pre-B cell stage and remaining through all stages of B cell differentiation prior to plasma cells. CD79b plays an important role in the regulation of antigen receptor function like the CD3 subunits do with TCR function on T lymphocytes.
Especificações
Target Species
Human
Specificity
CD79b
Other Names
B29 gene product, lg-b
Fluorochrome
APC
Regulatory Status
CE
Size
50 Tests
Format
Liquid
Flow Product Line
IOTest
Clone
CB3-1
Isotype
IgG1 Mouse
Clone Description
The CB3-1 antibody reacts with the external part of the CD79b molecule and is to be used in flow cytometry. This antibody is not suitable for intracytoplasmic staining. For this application the use of the CD79a antibody is recommended.
Cross Reactivity
Mink
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PRODUCT AVAILABILITY AND REGULATORY STATUS DEPENDS ON COUNTRY REGISTRATION PER APPLICABLE REGULATIONS
The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.
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