Kappa Chain Antigen

Kappa (κ) chain is a 25Kd polypeptide that results from papain cleavage of the IgG molecule, encoded by the human immunoglobulin kappa locus (IGK) on chromosome 2. The subunit structure of IgG comprises 2 light chains and 2 heavy chains. Each light chain is composed of two tandem immunoglobulin domains: a) one variable domain (VL) and b) one constant (CL) domain. While the VL show considerable sequence diversity the CL shows internal homology with repeating units. Anti-Kappa antibodies recognize the Kappa light chain of immunoglobulins expressed at the surface of a cellular subpopulation corresponding to approximately 2/3 of mature B lymphocytes in peripheral blood. This light chain is also found on the surface of a sub-population of immature bone marrow B lymphocytes.

Clone: Polyclonal  Isotype: F(ab’)2 Goat

Clone: Polyclonal Isotype: F(ab’)2 Rabbit

Choose a Kappa Chain Model

Product Line Specifications

Format Liquid
Specificity κ Chain
Clone Polyclonal-GAHK
Isotype F(ab’)2 Goat
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced C15623

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 

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